Active Pharmaceutical Ingredients (APIs) inoita basa rakakosha muindasitiri yemishonga uye ndiyo hwaro hwekutanga hwekugadzira mishonga yese.
Saizi yemusika weindasitiri yemishonga yeJapan iri pachinzvimbo chechipiri muAsia.Nekuwedzera kwemari yeR&D yeindasitiri yemishonga nezvimwe zvikonzero, zvinotarisirwa kuti musika weJapan APIs uchakura pamwero wakanyanya we7% kusvika 8% panosvika 2025. Pakati pavo, makambani emishonga akaita basa rakakura anosanganisira. Sun Pharmaceutical, Teva, Novartis International AG, Piramal Enterprises, uye Aurobindo.
Kusimukira kweindasitiri yemishonga yegeneric yekuJapan kwakatarisanawo nechimhingamupinyi chekusakwana kwakazvimirira kwekupihwa kwezvigadzirwa.Inoda kusvika 50% yezvigadzirwa zvayo zvemukati zvemaAPI zvinoshandiswa kugadzirwa kwemishonga yemazuva ano, uye vatengesi vepasi rose vanobva kunyika dzeAsia neEurope dzakadai seIndia, China, South Korea, Italy, Spain, Hungary neGermany.Kuti uderedze kutsamira kune anounzwa kunze kwenyika maAPI, Japan iri kutarisa kune yenzvimbo yeAPIs.
Sumitomo Pharmaceuticals, kambani yekutanga muJapan kugadzira mishonga yemakemikari ichishandisa advanced organic synthesis tekinoroji, inoronga kuvaka nyowani diki molecule mishonga APIs uye yepakati fekitori muOita Guta, Oita Prefecture.Chinangwa chikuru chepurojekiti ndechekuwedzera mukana wekugadzira API yekambani kuti isangane nekukura kuri kudiwa kwemhando yepamusoro API uye yepakati.
Chirimwa chitsva ichi chakarongerwa kuiswa mukushanda munaGunyana 2024. Dhipatimendi rayo rekuvandudza nekugadzira (CDMO) rinoshandisa tekinoroji yakasiyana kugadzira uye kupa maAPI mamorekuru nemapakati emakambani ekugadzira, uye kuona kutengesa kwekunze kwekutengesa.Nekuda kwekuda kwakasimba kwemapurojekiti matsva ekuvandudza zvinodhaka, musika wepasi rose wemishonga CDMO wakaramba uchikura.Inofungidzirwa kuti ikozvino pasi rose kukosha kwekutengeserana kwemishonga yeCDMO inenge 81 mabhiriyoni emadhora ekuAmerica, akaenzana ne10 trillion yen.
Ichivimba neayo yakanakisa yemhando yekusimbisa system uye yepasirese chain manejimendi mabhenefiti, Sumitomo Pharmaceuticals yakawedzera zvishoma nezvishoma bhizinesi rayo reCDMO mumakore uye yakamisa chinzvimbo chinotungamira muJapan.Miti yaro muGifu neOkayama ine diki yekugadzira.Kusimba kwakasimba kwekugadzira maAPIs uye epakati anodiwa kune molecular therapeutic drugs.Mugadziri wekondirakiti yemishonga yeJapan Bushu Corporation yakasvika pachibvumirano chekushandira pamwe neSuzuken Pharmaceutical Company muna Kubvumbi 2021 kuti ipe rubatsiro rutsva rwekuvandudza chigadzirwa kumakambani emishonga ane hunyanzvi arikuda kupinda mumusika weJapan.Bushu inotarisira kuita chibvumirano chekushandira pamwe chekugadzira zvakanangana mudzimba maAPIs, kuburikidza nekushandira pamwe kwemakambani maviri emishonga, kupa masevhisi ekutungamira kwekuda kwemishonga yakakosha, kusanganisira kukwidziridzwa kwevaridzi vemvumo / vane zvinodhaka kutamisa kubvunzana, kupinza, kuongororwa kwemusika, Kugadzira uye kupa, kuchengeterwa kuchengetedza uye kutakura, kuongororwa kwekusimudzira uye rubatsiro rwevarwere uye mamwe masevhisi.
Panguva imwecheteyo, Bushu Pharmaceuticals inokwanisa kuendesa mishonga kuvarwere panguva yese iyi nekushandisa mushonga wakakosha micro-cold chain monitoring system (Cubixx) yakagadziridzwa neSuzuken Co., Ltd. Pamusoro pezvo, Kambani yekuJapan yeAstellas Pharmaceutical yakaburitsa kuti maererano ne chirongwa chechitatu chekuwedzera kugadzirwa, hwaro hweAPI hwekugadzirwa kwemishonga isingachinjiki yakavambwa muToyama, Japan muna Ndira 2020 ichashandiswa kugadzira yekutanga Astellas Prograf's tacrolimus hydrate API.
Tacrolimus mushonga unodzivirira uye unobata kurambwa kwenhengo muvakuru nevana varwere vakagamuchira chiropa, itsvo, moyo (uye mapapu kubvumidzwa kutsva kweFDA muna 2021) kuisirwa.
Nguva yekutumira: Jun-03-2019
